Neuropsychology of Human Immunodeficiency Virus

Heather Adams, Ph.D.

October 29, 2003

A. What is HIV???

1) brief definition

2) Stages of HIV Infection

B. History & Epidemiologyof HIV in the United States

1) Earliest reports...

2) Centers for Disease Control (CDC) creates a definition for AIDS

3) Estimated number of cases, deaths over the past 2 decades

4) Worldwide....

5) Some slides...

C. HIV/AIDS and Neuropsychological Functioning

1) Terminology

a) Minor Cognitive Motor Disorder

b) Dementia

2) Subcortical Pattern of Cognitive Impairment

a) Neuropsychological Findings with HIV-positive Samples

i. areas of impairment

ii. areas of relative sparing

3) Case Presentation #1

4) Case Presentation #2

D. Neuropathology of HIV Infection

1) How it happens – how HIV impacts the brain

2) What happens? – what HIV does in the brain

E. HIV – related Neuropsychological Impairment & Everyday Functioning

1) Employment

2) Other Quality of Life indicators

F. Pediatric HIV/AIDS

1) Epidemiology

2) Abnormalities in the Developing Brain

3) Early vs. Late onset of HIV-related symptoms

4) Cognitive Development – Infants and School- Age Children

a. General IQ

b. Language Development

c. Motor Development

d. Social/Emotional Development

e. Medication Effects on Cognitive Functioning

G. HIV/AIDS Worldwide – some final numbers