Instructor: Peter G. Como, Ph.D., T & Th, 4:50 - 6:05 pm
Teaching Assistant: Scott Hunter, Ph.D.
BCS Office: 105 Meliora Hall; Classroom: 204 Meliora Hall
Neurology Office: 5-5221 Medical Center
Phone: 5-5130
Required Texts:
Fundamentals of Human Neuropsychology, B. Kolb & I.Q.
Whishaw, 4th Edition, 1996
Neuropsychology: A Clinical Approach, K.W. Walsh, 2nd Edition,
1994
Required Readings: articles on reserve in Carlson Library
Date Topic Reading Assignments*
Jan 21 Introduction & Overview
23 History of Neuropsychology Ch 1
28 Neuropsychological Assessment Ch 2 + articles
30 Functional Organization of the Brain (Dr. Hunter) Ch 3-7
Feb 4 Cortical Organization (Dr. Hunter) Ch 8-9
6 EXAM I
11 Behavioral Geography of the Brain - Occipital/Parietal Ch 11-12
13 Behavioral Geography of the Brain - Temporal Lobes Ch 13
18 Behavioral Geography of the Brain - Frontal Lobes Ch 14
20 Memory Functions (Dr. Rediess) Ch 16
25 Memory Assessment & Disorders (Dr. Rediess) articles
27 Language Function & Assessment Ch 17 + articles
Mar 4 Visual Neglect & Perceptual Disorders Ch 19 + articles
6 EXAM II
11 Spring Break
13 Spring Break
18 Introduction to Neuropsychological Syndromes Ch 18 + articles
20 Neurodegenerative Disorders - Cortical Dementias Ch 25 + articles
25 Neurodegenerative Disorders - Subcortical Dementias Ch 25 + articles
27 Subcortical Dementia (Como) articles
Apr 1 TBI/CHI (Wong) Ch 24 + articles
3 Epilepsy (Dr. Langfitt) Ch 24 + articles
8 EXAM III
10 Wada tapes (Como) articles
15 Neurotox. (Rahill) articles
17 TS/ADHD (Como) articles
22 LD (Palumbo) Ch 22 articles
24 Schizophrenia (Silverstein) articles
29 Neuro Exam (Siderowf) articles
May 1 Forensic articles
6 NO CLASS - Reading Period
FINAL EXAM: Monday, May 12 at 4:50-6:05 pm in GAV 208
*Additional articles will be assigned for some topics and put on reserve in
Carlson Library
This course will introduce the student to the field of clinical neuropsychology which bridges the domains of neurology, neuroscience and clinical psychology. It begins with a general overview and history of clinical neuropsychology. Then, principles of neuropsychological assessment and the interpretation of cognitive and behavioral findings as they relate directly to brain dysfunction will be discussed. The remainder of the course will be "syndrome" oriented and will focus on specific neurological syndromes including: neurodegenerative disorders, cerebrovascular disorders, memory disorders, epilepsy, head trauma, toxic disorders, infectious processes, pediatric neuropsychology, psychiatric syndromes, and forensic neuropsychology. In addition to conventional course instruction (e.g., lectures, readings), patient presentations (videotape and in-person interviews) will be used.
The textbook is a good introductory resource but does not adequately cover in-depth the clinical syndromes we will be discussing during the course. Some of the chapters will not be required and you will not be examined on the non-assigned chapters.
The reading assignments will heavily supplement this course, notably during the latter part of the course when clinical syndromes are discussed in greater detail. It is up to you to understand the main points of these articles and let us know if you need more clarification.
Some of the information covered in the textbook will not be directly discussed in the classroom. Therefore, it is your responsibility to read all of the assigned chapters and readings. You will be examined on this material.
Grades will be determined from three tests and a final examination. Each test will count towards 25% of your grade. After each test, we will give you an overview of where you stand in terms of the number of "points" you have accumulated. No predetermined "A", "B", "C", etc grades will be given; grading will be on a "curve" so that your performance is matched against that of your peers.
The tests and final exam will consist of multiple choice. We may decide to include short essay questions after EXAM I based on how students perform. The material on the exams will be determined from we cover in class AND reading assignments. The tests and final exam are not necessarily cumulative, but you are expected to understand the basic concepts from previous lectures.
Neuropsychology Web Page: http//: www.premier.net/~cogito/neuropsy.html
This is a centralized web page with links to many useful resources for neuropsychology, including readings, brain anatomy computer modules, etc. May be worth surfing in your abundant spare time.
ASSIGNED SUPPLEMENTAL READINGS FOR BCS/PSY 242
all articles are on reserve in Rush Rhees Library
Neuropsychological Assessment
Lezak, Neuropsychological Assessment, 3rd Edition, Ch 4-6, 8
Memory (for Redeiss lectures, 2/20/97 & 2/25/97)
Butters, N., et al. (1995). Clinical assessment of memory disorders in amnesia and dementia. Annual Review of Psychology, 46, 493-523.
Multiple Sclerosis (for Weinstein lecture, 3/4/97)Rao, S., et al. (1991). Cognitive dysfunction in multiple sclerosis. I. Frequency, patterns, and prediction. Neurology, 41, 685-691.
Rao, S., et al. (1991). Cognitive dysfuntion in multiple sclerosis. II. Impact on employment and social functioning. Neurology, 41, 692-696.
Sobel, R. (1995). The pathology of multiple sclerosis. Neurologic Clinics, 13, 1-21.
Murray, T. (1995). The psychosocial aspects of multiple sclerosis. Neurologic Clinics, 13, 197-223.
LanguageBenson, D. (1993). Aphasia. In K. Heilman & E. Valenstein (Eds)., Clinical Neuropsychology, 3rd edition. (pp. 17-36). NY: Oxford University Press.
Damasio, A. & Damasio, H. (1992). Brain and language. Scientific American, 267, 88-95.
Pugh, K., et al. (1996). Cerebral organization of component processes in reading. Brain, 119, 1221-1238. (also for Learning Disabilities lecture 4/22/97)
Visual Neglect and Perceptual DisordersBenton, A. & Tranel, D. (1993). Visuoperceptual, visuospatial, and visuoconstructive disorders. In K. Heilman & E. Valenstein (Eds.), Clinical Neuropsychology, 3rd edition. (pp. 165-214). NY: Oxford University Press.
Heilman, K., et al. (1993). Neglect and related disorders. In K. Heilman & E. Valenstein (Eds.), Clinical Neuropsychology, 3rd edition. (pp. 279-336). NY: Oxford University Press.
AIDS and HIV Dementia (for Hunter lecture, 3/20/97)
Glass, J. & Johnson, R. (1996). Human immunodeficiency virus and the brain. Annual Review of Neuroscience, 19, 1-26.
Kelly, M. et al. (1996). Neuropsychological findings in HIV infection and AIDS. In I. Grant & K. Adams (Eds.), Neuropsychological Assessment of Neuropsychiatric Disorders, 2nd edition. (pp. 403-422).
Neuropsychological Syndromes (relevant for 3/27/97)
Bondi, M., et al. (1996). The neuropsychology of dementia. In I. Grant & K. Adams (Eds.), Neuropsychological Assessment of Psychiatric Disorders, 2nd edition. (pp. 164-199). NY: Oxford University Press.
Brandt, J. & Butters, N. (1996). Neuropsychological characteristics of Huntington's disease. In I. Grant & K. Adams (Eds.), Neuropsychological Assessment of Psychiatric Disorders, 2nd edition. (pp. 312-341). NY: Oxford University Press.
Heilman, K., et al. (1993). Emotional disorders associated with neurological diseases. In K. Heilman & E. Valenstein (Eds.), Clinical Neuropsychology, 3rd edition. (pp. 461-498). NY: Oxford University Press.
Selkoe, D. (1992). Aging brain, aging mind. Scientific American, 267, 135-142.
Traumatic & Closed Head Injury (for Wong lecture, 4/1/97)Strub, R. & Black, F.W. (1988). Closed head trauma. Neurobehavioral disorders: A clinical approach. (pp. 313-348). Philadelphia, PA: F.A. Davis.
Epilepsy & Seizure Disorders (for Langfitt lecture, 4/3/97)
Dodrill, C. Neuropsychology of epilepsy. (pp. 366-370).
Gazzaniga, M. The split brain in man.
Scoville, W. & Milner, B. (1957). Loss of recent memory after bilateral hippocampal lesions. Journal of Neurology, Neurosurgery, and Psychiatry, 20, 11-21.
Neurotoxicology (for Rahill lecture, 4/15/97)
Weiss, B. (1983, November). Behavioral toxicology and environmental health science. American Psychologist, 1174-1187.
White, R., et al. (1992). Neurobehavioral effects of toxic exposures. (pp. 1-39, not complete chapter). In R. White (Ed)., Clinical Syndromes in Adult Neuropsychology: The Practitioner's Handbook. NY: Elsevier Science Publishers.
Pediatric Neuropsychology Lectures:
Tourette Syndrome/ADHD (for Como lecture, 4/17/97)
Cantwell, D. (1996). Attention deficit disorder: A review of the past 10 years. Journal of the American Academy of Child and Adolescent Psychiatry, 35, 978-987. (DP)
Como, P. (In press). Neuropsychological tests for obsessive-compulsive disorder and attention deficit hyperactivity disorder. In J. Jankovic (Ed.), Tourette's syndrome. Neurologic Clinics.
Silverstein, S., et al. (1995). Multiple sources of attentional dysfunction in adults with Tourette's syndrome: Comparison with Attention deficit-hyperactivity disorder. Neuropsychology, 9, 157-164.
Yeates, K. & Bornstein, R. (1994). Attention deficit disorder and neuropsychological functioning in children with Tourette's syndrome. Neuropsychology, 8, 65-74.
Learning Disabilities (for Palumbo lecture, 4/22/97)
Hynd, G., et al. Neuropsychological assessment in clinical child psychology. (pp. 35-86).
Spreen, O., et al. (1995). Learning disorders. Developmental Neuropsychology. (pp. 471-495). NY: Oxford University Press.
Witelson, S. (1987). Neurobiological aspects of language in children. Child Development, 58, 653-688.
Schizophrenia (for Silverstein lecture, 4/24/97)
Gershon, E. & Reider, R. (1992). Major disorders of mind and brain. Scientific American, 267, 126-133.
Randolph, C., et al. (1993). The neuropsychology of schizophrenia. In K. Heilman & E. Valenstein (Eds.), Clinical Neuropsychology, 3rd edition. (pp. 499-522). NY: Oxford University Press.
Neurological Examination (for Siderowf lecture, 4/29/97)
Malloy, P. & Nadeau, S. The neurological examination and related diagnostic procedures in behavioral neurology and neuropsychology. (pp. 105-133).
Forensic Neuropsychology (as scheduled, readings to be assigned)