Description

Syllabus

Schedule

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Blackboard

NSC 243: Lecture Schedule

Only students who are enrolled in the course may access the readings online. You must be logged into Blackboard to download the course readings.

All unlinked chapters and page numbers are from Siegel, et al.

Date Topic Readings
09/01 Neurochemistry: An Historical Overview
Introduction to Chemically Mediated Synaptic Transmission
Ch 10
Part One—Synaptic Neurochemistry: Presynaptic Mechanisms
09/03 Acetylcholine Ch 11
Cooper, Bloom, & Roth 2003 Ch 7
09/08 Catecholamines Ch 12
09/10 Serotonin Ch 13
09/15 Glutamic Acid Ch 15
09/17 GABA & Glycine Ch 16
09/22 Peptides, Transmitter Co-existence Ch 18
Furness et al. 1989
09/24 Other Chemical Messengers: Retrograde Messengers & Extraneuronal Messengers Ch 17, 27, 52
Snyder & Ferris 2000
09/29 EXAM ONE  
Part Two—Synaptic Neurochemistry: Postsynaptic Cell Signaling Mechanisms
10/01 Receptors: Recognition Site McGonigle & Molinoff; Cooper, Bloom, & Roth 2003 Ch 4
10/06 Receptor-Effector Mechanisms: Ligand-gated Ion Channels Ch 11, pp. 197-202 (Nicotinic Receptor)
Ch 15, pp. 273-280 (Glutatmate Receptors)
Ch 16, pp. 293-298 (GABA Receptors)
10/08 Receptor-Effector Mechanisms: Second Messenger Systems Chs 19, 20, 21
Ch 12, pp. 217-223 (Catecholamine Receptors)
Ch 13, pp. 240-247 (Serotonin Receptors)
Ch 11, pp. 203-208 (Muscarinic Receptors)
Ch 17, pp. 312-314 (Adenosine Receptors)
Ch 18, pp. 326-328 (Peptides)
10/13 Phosphorylation & Brain Function Chs 23-24
10/15 Importance of Calcium to Brain Function Ch 22
10/20 Transmitter Roles BS (Before Synapses) Weiss, Maness, & Lauder 1998; Ben-Ari 2002; Represa & Ben-Ari 2005
10/22 EXAM TWO  
Part Three—Metabolic Chemistry
10/27 Carbohydrates & Energy Metabolism Ch 31
Laterra et al. 1999
10/29 Amino Acids & Protein Function in Brain Ch 26
Ch 40, pp. 668-673
Hymen & Nestler 2004; Borelli et al. 2008; Zamore & Haley 2005
11/03 Brain Lipids: Multiple Roles Chs 3, 33
Ch 56, pp. 919-921 (Cannanbinoids)
11/05 Survival & Death of Neurons Chs 32, 35
11/10 Stem Cells in the Brain: Dr. Lisa Opanashuk Ch 29
Zhao, Deng, & Gage 2008; Kempermann 2008
11/12 EXAM THREE  
Part Four—Applied Neurochemistry: Mini Symposia
11/17 Symposium One  
11/19 Symposium Two  
11/24 Sex Differences in the Brain: Carol Kellogg  
11/26 Thanksgiving: NO CLASS  
12/01 Symposium Three  
12/03 Symposium Four  
12/08 Symposium Five  
12/10 Symposium Six  

Symposia Titles

  • Neurochemical Mechanisms of Plasticity: Learning and Memory
    Reading: Ch 53
  • Basal Ganglia Function and Dysfunction
    Reading: Ch 46
  • Addiction
    Reading: Ch 56
  • Neurochemistry of Schizophrenia
    Reading: Ch 54
  • Mood and Anxiety Disorders
    Reading: Ch 55
  • Neurobiology of the Epilepsies
    Reading: Ch 37

The date of each symposium will be announced on Sept. 17

Tentative Workshop Schedule

Workshops will be held on Tuesday evening, time to be arranged. Workshops will be held in Meliora 111, the room where the Neurobiology lab is held.

  • Workshop 1: Tuesday, Sept. 15
  • Workshop 2: Tuesday, Sept. 22
  • Exam 1: Tuesday Sept. 29
  • Workshop 3: Tuesday, Oct. 13
  • Workshop 4: Tuesday, Oct. 20
  • Exam 2: Thursday Oct. 22
  • Workshop 5: Tuesday, Nov. 3
  • Workshop 6: Tuesday, Nov. 10
  • Exam 3: Thursday, Nov. 12

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